{"id":17037,"date":"2025-12-11T10:59:46","date_gmt":"2025-12-11T10:59:46","guid":{"rendered":"https:\/\/prakriyahospitals.com\/hospital\/?p=17037"},"modified":"2025-12-15T12:03:19","modified_gmt":"2025-12-15T12:03:19","slug":"cervical-cancer-screening-and-vaccination","status":"publish","type":"post","link":"https:\/\/prakriyahospitals.com\/hospital\/cervical-cancer-screening-and-vaccination\/","title":{"rendered":"CERVICAL CANCER SCREENING AND VACCINATION"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">&#8220;Cervical cancer is the most curable and preventable cancer &#8221; Let&#8217;s get aware.\u2026<\/h4>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"527\" height=\"287\" src=\"https:\/\/prakriyahospitals.com\/hospital\/wp-content\/uploads\/2025\/12\/CERVICAL-CANCER-SCREENING-AND-VACCINATION.jpg\" alt=\"\" class=\"wp-image-17038\" srcset=\"https:\/\/prakriyahospitals.com\/hospital\/wp-content\/uploads\/2025\/12\/CERVICAL-CANCER-SCREENING-AND-VACCINATION.jpg 527w, https:\/\/prakriyahospitals.com\/hospital\/wp-content\/uploads\/2025\/12\/CERVICAL-CANCER-SCREENING-AND-VACCINATION-300x163.jpg 300w\" sizes=\"(max-width: 527px) 100vw, 527px\" \/><\/figure>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Cervical cancer remains one of the leading causes of female mortality globally, affecting almost half a million women every year.<\/li>\n\n\n\n<li>While the overall mortality rate has significantly decreased in high-income countries during the last decades, it remains high in middle- and low-income countries, with 88% of deaths.<\/li>\n\n\n\n<li>The most prevalent risk factors for cervical cancer include infection with human papillomavirus (HPV) , infection with Human Immunodeficiency Virus (HIV) or other causes of immunosuppression , in utero exposure to diethylstilbestrol (DES) and a previous history of precancerous cervical lesions, such as cervical intraepithelial neoplasia (CIN) grade 2 or 3.<\/li>\n\n\n\n<li>Screening for cervical cancer aims primarily at the detection of precancerous lesions to prevent their progression to invasive disease; cytology was the most commonly used method.<\/li>\n\n\n\n<li>The development and implementation of effective vaccines against high-risk HPV subtypes, especially <strong>16 and 18<\/strong>, have  significantly reduced HPV-related precancerous lesions<\/li>\n\n\n\n<li>However, while this is a highly effective strategy to drastically reduce the incidence of cervical cancer, implementation still remains at a suboptimal level, especially in <strong>low-income countries.<\/strong><\/li>\n<\/ul>\n\n\n\n<p><strong>SOME IMPORTANT SCREENING RECOMMENDATIONS<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>ASCO<\/strong><\/td><td><strong>WHO<\/strong><\/td><td>&nbsp;<\/td><\/tr><tr><td><strong>SCREENING METHODS<\/strong><\/td><td>HPV testing -VIA<\/td><td>-HPV testing -VIA -Cytology<\/td><\/tr><tr><td><strong>AGES &lt;21<\/strong><\/td><td>Screening not recommended<\/td><td>Screening not recommended<\/td><\/tr><tr><td><strong>AGES 21\u201329<\/strong><\/td><td>Age 21\u201324 years \u2192 Screening not recommended Age &gt;25 years \u2192 Maximal: HPV testing every 5 years Enhanced: screening not recommended Limited: screening not recommended Basic: Screening is not recommended<\/td><td>Screening not recommended<\/td><\/tr><tr><td><strong>AGES 30\u201365<\/strong><\/td><td>Maximal: HPV testing every 5 years Enhanced: HPV testing every 5 years or every 10 years after two consecutive negative results Ages 30\u201349 \u2192 Limited: HPV testing every 10 years Basic: HPV testing every 10 years or VIA every 5\u201310 years<\/td><td>Age 30\u201350 Primary HPV testing with or without HPV 16\/18 genotyping every 5\u2013 10 years Alternatively: -VIA every 3 years -Cytology every 3 years Age 50\u201365 Screening may be offered in women with no screening history if feasible<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>AGES &gt;65<\/strong><\/td><td>Maximal: individualization, screening up to 70 years Enhanced: Screening is not recommended if adequate previous screening Limited: screening not recommended Basic: screening is not recommended<\/td><td>Screening not recommended<\/td><\/tr><tr><td><strong>ADEQUATE SCREENING<\/strong><\/td><td>Maximal: negative results in the last 15 years Enhanced: negative results in the last 15 years<\/td><td>2 consecutive negativeresults<\/td><\/tr><tr><td><strong>HISTORY OFPRECANCEROUSLESION<\/strong><\/td><td>Maximal: If (+) at 60 years, screening for at least 10 years<\/td><td>In CIN2\/3: Repeat HPV DNA in 12 months If negative, routine screening In CIN3+: HPV DNA annually for 3 years after treatment and then return to routine screening<\/td><\/tr><tr><td><strong>HISTORY OFHYSTERECTOMYWITHOUT PREVIOUSCIN2\/3<\/strong><\/td><td>Screening not recommended<\/td><td>Not mentioned<\/td><\/tr><tr><td><strong>ABNORMAL RESULTS<\/strong><\/td><td>Enhanced: In HPV DNA (+) \u2192 hrHPV and\/or cytology In negative results \u2192 repeat HPV in 12 months In positive results \u2192 colposcopy Limited: In HPV DNA (+) \u2192 Cytology or hrHPV or VIA Abnormal cytology \u2192 colposcopy or<\/td><td>If negative \u2192 repeat HPV at 24 months (if negative, routine screening) In primary cytology (+) and colposcopy (-) \u2192 HPV DNA at 12 months (if negative, routine screening)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><\/td><td colspan=\"2\">&nbsp;VAT Basic: In HPV DNA (+) \u2192 VAT<\/td><\/tr><tr><td><strong>IMMUNODEFICIENCY<\/strong><\/td><td>Twice as many screenings as the general population<\/td><td>If negative \u2192 repeat HPV at 12 months (if negative, routine screening) In primary cytology (+) and colposcopy (-) \u2192 HPV DNA at 12 months (if negative, routine screening) If treated for CIN2+ \u2192 two consecutive negative HPV DNA results every 12 months before routine screening<\/td><\/tr><tr><td><strong>VACCINATION<\/strong><\/td><td>Same screening<\/td><td>Not mentioned<\/td><\/tr><tr><td><strong>PREGNANCY<\/strong><\/td><td>Not mentioned<\/td><td>Not mentioned<\/td><\/tr><tr><td><strong>SEXUAL ACTIVITY<\/strong><\/td><td>Not mentioned<\/td><td>Not mentioned<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>*hr- HIGH RISK<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">VACCINATION SCHEDULE <\/h3>\n\n\n\n<p><strong>WHO now recommends:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>A one or two-dose schedule <\/strong>for girls aged <strong>9-14 years<\/strong><\/li>\n\n\n\n<li><strong>A one or two-dose schedule <\/strong>for girls and women aged <strong>15-20 years<\/strong><\/li>\n\n\n\n<li>Two doses with a 6-month interval for women <strong>older than 21 years <\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">GARDASIL:<\/h3>\n\n\n\n<h3 class=\"wp-block-heading\">INDICATION:<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>GARDASIL 9 <\/strong>helps protect individuals ages 9 to 45 against the following diseases caused by <strong>9 types of HPV STRAINS: <\/strong>cervical, vaginal, and vulvar cancers in females, anal cancer, certain head and neck cancers, such as throat and back of mouth cancers and genital warts in both males and females.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">ROUTE OF ADMINISTRATION:<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>GARDASIL 9 <\/strong>is a shot that is usually given in the arm muscle.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">DOSAGE:<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>For persons 9 through 14 years of age, <strong>GARDASIL 9 <\/strong>can be given using a <strong>2-dose or 3-dose schedule.<\/strong><\/li>\n\n\n\n<li>For the 2-dose schedule, the second shot should be given 6-12 months after the first shot. If the second shot is given less than 5 months after the first shot, a third shot should be given at least 4 months after the second shot.<\/li>\n\n\n\n<li>For the 3-dose schedule, the second shot should be given 2 months after the first shot and the third shot should be given 6 months after the first shot.<\/li>\n\n\n\n<li>For persons 15 through 45 years of age, <strong>GARDASIL 9 <\/strong>is given using a 3-dose schedule; the second shot should be given 2 months after the first shot and the third shot should be given 6 months after the first shot.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">CERVAVAC:<\/h3>\n\n\n\n<h2 class=\"wp-block-heading\">INDICATION:<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CERVAVAC <\/strong>is indicated in girls and women 9 through 26 years of age for the prevention of the following diseases caused by Human Papillomavirus (HPV) types, included in the vaccine:<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Cervical, vulvar, vaginal, and anal cancer caused by HPV types 16 and 18.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Genital warts (condyloma acuminata) caused by HPV types 6 and 11.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CERVAVAC <\/strong>is indicated in boys and men 9 through 26 years of age for the prevention of the following diseases caused by HPV types included in the vaccine:<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Anal cancer caused by HPV types 16 and 18.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Genital warts (condyloma acuminata) caused by HPV types 6 and 11.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">ROUTE OF ADMINISTRATION:<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CERVAVAC <\/strong>should be administered intramuscularly in the deltoid region of the upper arm or in the higher anterolateral area of the thigh.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">DOSAGE:<\/h3>\n\n\n\n<p><strong>Individuals 9 to 14 years of age<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CERVAVAC <\/strong>should be administered according to a 2-dose schedule (0.5 ml at 0, 6 months).<\/li>\n\n\n\n<li>Individuals 15 to 26 years of age <strong>CERVAVAC <\/strong>should be administered according to a 3-dose (0.5 ml at 0, 2, 6 months) schedule.<\/li>\n\n\n\n<li>The second dose should be administered at least one month after the first dose and the third dose should be administered at least 3 months after the second dose. All three doses should be given within a 1-year period.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Paediatric population <\/strong>:<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The safety and efficacy of <strong>CERVAVAC <\/strong>in children below 9 years of age have not been established. No data are available.<\/li>\n\n\n\n<li>It is recommended that individuals who receive a first dose of <strong>CERVAVAC <\/strong>complete the vaccination course with <strong>CERVAVAC.<\/strong><\/li>\n\n\n\n<li>The need for a booster dose has not been established.<br><br><\/li>\n<\/ul>\n\n\n\n<p><strong>Dr. Mounika Reddy C<\/strong><\/p>\n\n\n\n<p><br>MBBS, MD (Radiation Oncology), DM (Medical Oncology)<\/p>\n\n\n\n<p>Consultant &#8211; Medical Oncologist<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Cervical cancer is the most curable and preventable cancer &#8221; Let&#8217;s get aware.\u2026 SOME IMPORTANT SCREENING RECOMMENDATIONS ASCO WHO &nbsp; SCREENING METHODS HPV testing -VIA -HPV testing -VIA -Cytology AGES &lt;21 Screening not recommended Screening not recommended AGES 21\u201329 Age 21\u201324 years \u2192 Screening not recommended Age &gt;25 years \u2192 Maximal: HPV testing every 5 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":17039,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[59],"tags":[],"class_list":["post-17037","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-oncology"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>CERVICAL CANCER SCREENING AND VACCINATION - Prakriya Hospitals<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/prakriyahospitals.com\/hospital\/cervical-cancer-screening-and-vaccination\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CERVICAL CANCER SCREENING AND VACCINATION - Prakriya 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